Rat and poultry feeding studies with soybean meal produced from imidazolinone-tolerant (CV127) soybeans. (February 2016)

• Record Type: Journal Article
• Authors: He, Xiaoyun; de Brum, Paulo A.R.; Chukwudebe, Amechi; Privalle, Laura; Reed, Andrew; Wang, Yanqing; Zhou, Cui; Wang, Cuiyan; Lu, Jing; Huang, Kunlun; Contri, Daniela; Nakatani, Andreia; de Avila, Valdir S.; Klein, Claudete H.; de Lima, Gustavo J.M.M.; Lipscomb, Elizabeth A.
• Is Part Of: Food and chemical toxicology. Volume 88(2016)
• Page Start: 48
• Page End: 56
• Publication Date: 2016-02
• Subjects: Acetohydroxyacid synthase -- Broiler study -- Genetically modified crop -- Herbicide-tolerant crop -- Nutritional study -- Subchronic feeding study; AHAS Acetohydroxyacid synthase -- ALT alanine aminotransferase -- ALB albumin -- ALP alkaline phosphatase -- AST aspartate aminotransferase -- PLT blood platelet count -- BUN blood urea nitrogen -- Ca calcium -- CHOL cholesterol -- CREA creatinine -- GM genetically modified -- GMO genetically modified organism -- GLUC glucagon -- GLP Good Laboratory Practices -- HCT hematocrit -- HGB hemoglobin -- ITAL Institute of Food Technology -- ILSI International Life Sciences Institute -- LDH lactate dehydrogenase -- MCH mean corpuscular hemoglobin -- MCHC mean corpuscular hemoglobin concentration -- MCV mean corpuscular volume -- MPV mean platelet volume -- AMEn nitrogen-corrected apparent metabolizable energy -- P phosphorous -- RBC red blood cell -- SP Santo Antônio da Posse -- TPROT total protein -- TRIG triglycerides -- U.S. United States -- WBC white blood cell; Toxicology -- Periodicals; Food poisoning -- Periodicals; Food Poisoning -- Periodicals; Toxicology -- Periodicals; Toxicologie -- Périodiques; Intoxications alimentaires -- Périodiques; Food poisoning; Toxicology; Periodicals; Electronic journals; 615.9
• DOI: 10.1016/j.fct.2015.12.012
• Languages: English
• ISSNs: 0278-6915

Abstract

Abstract: The safety and nutritional properties of CV127 soybeans were evaluated in rat and broiler feeding studies. Some episodic differences were observed between rats fed CV127, Conquista, and the standard diet for the endpoints examined. None of these differences were considered treatment related, adverse, or biologically meaningful. In general, birds fed diets containing CV127, Conquista, or Monsoy 8001 showed no significant differences in growth and performance response variables. Chickens fed diets containing Coodetec 217 had lower body weight and weight gain for all developmental periods compared to CV127, but no significant differences were found in feed conversion for the two diets during any development period. The results of both feeding studies demonstrate that CV127 soybeans are as safe, wholesome, and nutritionally valuable as the other soybean meals tested, including those varieties for which histories of safe use have been established and well documented. Highlights: No significant differences were observed in body weight change for male or female rats when comparing CV127 versus control. No treatment related effects were found between rats fed CV127 versus control for hematology or serum chemistry values. Broilers fed a diet comprised of CV127 yielded growth performance at least equivalent to control and reference diets.