Two-photon fluorescent probe for peroxynitrite. Issue 6 (10th February 2016)

• Record Type: Journal Article
• Authors: Park, JinHee; Heo, Cheol Ho; Kim, Hwan Myung; Hong, Jong-In
• Is Part Of: Tetrahedron letters. Volume 57:Issue 6(2016)
• Page Start: 715
• Page End: 718
• Publication Date: 2016-02-10
• Subjects: Two-photon fluorescence probe -- Peroxynitrite -- Dearylation reaction; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2016.01.025
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: Peroxynitrite (ONOO − ), a strong oxidant found in biological systems, and an increase in its levels is related to numerous diseases, immune responses, and redox regulation of signaling pathways. Herein, we report a new two-photon probe that sensitively and selectively detects ONOO − among other ROS/RNSs (reactive oxygen/nitrogen species) using peroxynitrite-triggered dearylation reaction.