An efficient method to synthesize novel 5-O-(6′-modified)-mycaminose 14-membered ketolides. Issue 2 (14th January 2016)
- Record Type:
- Journal Article
- Title:
- An efficient method to synthesize novel 5-O-(6′-modified)-mycaminose 14-membered ketolides. Issue 2 (14th January 2016)
- Main Title:
- An efficient method to synthesize novel 5-O-(6′-modified)-mycaminose 14-membered ketolides
- Authors:
- Wang, A-Peng
Liu, Chao
Yang, Shuang
Zhao, Zhehui
Lei, Pingsheng - Abstract:
- Abstract: A new and facile procedure was developed to synthesize novel 5- O -(6′-modified)-mycaminose 14-membered ketolides by adopting different protective strategies and comparing various glycosylation conditions. Seven trichloroacetimidate donors which had different types of substituent groups at C-6 position were synthesized to couple with the erythronolide. Nine novel 5- O -(6′-modified)-mycaminose 14-membered ketolides were obtained to verify the utility of the method. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 2(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 2(2016)
- Issue Display:
- Volume 72, Issue 2 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 2
- Issue Sort Value:
- 2016-0072-0002-0000
- Page Start:
- 285
- Page End:
- 297
- Publication Date:
- 2016-01-14
- Subjects:
- Ketolides -- Desosamine mimetics -- Mycaminose -- Glycosylation -- Modification
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2015.11.029 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 2281.xml