Two new diketopiperazines and a new glucosyl sesterterpene from Alternaria alternata, an endophytic fungi from Ceratostigma griffithii. (December 2015)

• Record Type: Journal Article
• Authors: Guo, Da-Le; Zhao, Min; Xiao, Shi-Ji; Xia, Bing; Wan, Bo; Gu, Yu-Cheng; Ding, Li-Sheng; Zhou, Yan
• Is Part Of: Phytochemistry letters. Volume 14(2015:Dec.)
• Page Start: 260
• Page End: 264
• Publication Date: 2015-12
• Subjects: Ceratostigma griffithii -- Alternaria alternata -- Diketopiperazine -- 24-α-d-glucosyl-(−)-terpestacin; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2015.10.024
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Two new diketopiperazine derivatives (1 -2 ) were isolated from Alternaria alternata . A new glucosyl sesterterpene (3 ) was isolated from Alternaria alternata . All the compounds were assayed for antimicrobial activity. Abstract: Two diketopiperazine derivatives, altenarizines A (1 ) and B (2 ), and a new glucosyl sesterterpene, 24-α-d -glucosyl-(−)-terpestacin (3 ), together with two known phytotoxic sesterterpenes, (−)-terpestacin (4 ) and fusaproliferin (5 ), were isolated from the fermentation broth of an endophytic fungus Alternaria alternata, which was obtained from the fresh root of Ceratostigma griffithii . Structures of all the isolates were identified by spectroscopic data.