Scanning proton beam therapy reduces normal tissue exposure in pelvic radiotherapy for anal cancer. Issue 3 (December 2015)

• Record Type: Journal Article
• Authors: Anand, Aman; Bues, Martin; Rule, William G.; Keole, Sameer R.; Beltran, Chris J.; Yin, Jun; Haddock, Michael G.; Hallemeier, Christopher L.; Miller, Robert C.; Ashman, Jonathan B.
• Is Part Of: Radiotherapy and oncology. Volume 117:Issue 3(2015:Dec.)
• Page Start: 505
• Page End: 508
• Publication Date: 2015-12
• Subjects: Spot scanning proton planning -- Whole pelvis proton therapy -- Anal cancer -- Bone marrow sparing; Oncology -- Periodicals; Radiotherapy -- Periodicals; Tumors -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiothérapie -- Périodiques; Cancérologie -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9940642
• DOI: 10.1016/j.radonc.2015.10.027
• Languages: English
• ISSNs: 0167-8140

Abstract

Abstract: An inter-comparison planning study between photon beam therapy (IMRT) and scanning proton beam therapy (SPBT) for squamous cell carcinoma of the anus (SCCA) is presented. SPBT plans offer significant reduction (>50%, P = 0.008) in doses to small bowel, and bone marrow thereby offering the potential to reduce bowel and hemotoxicities.