Impact of the automatic rounding-off function of the computerized physician order entry system on the ordering time and dose dispersion of chemotherapeutic drugs in regimens for hematologic malignancies. Issue 1 (January 2016) - Tsuda, Kenji
Highlights: We developed computerized physician order entry with automatic rounding function. Automatic rounding function shortened the ordering time of chemotherapeutic drugs. Automatic rounding function reduced the dose dispersion of chemotherapeutic drugs. Abstract: Introduction: EGMAIN-GX is the computerized physician order entry system used in Japan. The automatic rounding-off of the calculated dose of chemotherapeutic drugs is an update in version 4, compared to version 2. We conducted a comparative study between EGMAIN-GX versions 2 and 4 to estimate the effect of the automatic rounding-off function on ordering time and dose dispersion. Methods: Twelve hematologists ordered 5 predefined chemotherapeutic regimens most commonly used in treating hematologic malignancies, twice for each regimen. Results: EGMAIN-GX version 4 significantly reduced ordering times compared to version 2 (635 s vs. 259 s, p < 0.01). EGMAIN-GX version 4 also yielded a significantly higher ratio of actual to ideal doses of chemotherapeutic drugs than did version 2 (1.0097 and 0.9997, respectively; p < 0.01) and a lower standard deviation (0.0275 and 0.0290, respectively). Conclusions: The automatic rounding-off function could decrease the ordering time and dose dispersion of chemotherapeutic drugs.