Alarming rates of virological failure and drug resistance in patients on long-term antiretroviral treatment in routine HIV clinics in Togo. (28th November 2015)

• Record Type: Journal Article
• Authors: Konou, Abla A.; Dagnra, Anoumou Y.; Vidal, Nicole; Salou, Mounerou; Adam, Zakillatou; Singo-tokofai, Assétina; Delaporte, Eric; Prince-david, Mireille; Peeters, Martine
• Is Part Of: AIDS. Volume 29:Number 18(2015)
• Publication Date: 2015-11-28
• Subjects: AIDS (Disease) -- Periodicals; Acquired Immunodeficiency Syndrome; AIDS (Disease); Periodicals; Periodicals; 616.9792005
• DOI: 10.1097/QAD.0000000000000906
• Languages: English
• ISSNs: 0269-9370

Abstract

Abstract : Information on efficacy of long-term antiretroviral treatment (ART) exposure in resource-limited countries is still scarce. In 767 patients attending routine HIV centers in Togo and receiving first-line ART for more than four years, 42% had viral load greater than 1000 copies/ml and either were on a completely ineffective ART regime or were with only a single drug active. The actual conditions to ensure lifelong ART in resource-limited countries can have dramatic long-term outcomes.