Focal liver lesions detection: Comparison of respiratory-triggering, triggering and tracking navigator and tracking-only navigator in diffusion-weighted imaging. Issue 10 (October 2015)

• Record Type: Journal Article
• Authors: Bouchaibi, Said El; Coenegrachts, Kenneth; Bali, Maria Antonietta; Absil, Julie; Metens, Thierry; Matos, Celso
• Is Part Of: European journal of radiology. Volume 84:Issue 10(2015)
• Page Start: 1857
• Page End: 1865
• Publication Date: 2015-10
• Subjects: BH breath-hold -- DWI diffusion-weighted imaging -- FLL focal liver lesion -- MRI magnetic resonance imaging -- RT respiratory-triggering -- SE-EP spin-echo echo-planar -- TRON tracking only navigator -- TT trigerring and tracking; Liver -- Focal liver lesions -- Diffusion-weighted MRI -- Respiratory synchronization -- Navigators; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2015.06.018
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: Tracking navigator had more artefacts than respiratory triggered or trigger & track navigator images. Focal liver lesions detection was similar with respiratory trigger, trigger & track or tracking navigator. Sensitivity to detect focal liver lesions reached 89% (363/409) with trigger & track images. Inter-observer agreement in detecting focal liver lesions was very good k > 0.84 in b = 10 s/mm 2 images. For lesions <10 mm trigger & track detection was superior than tracking navigator ( p = 0.03, reader 2). Abstract: Purpose: To compare low b value (10 s/mm 2 ) spin-echo echo-planar (SE-EP) diffusion-weighted imaging (DWI) acquired with respiratory-triggering (RT), triggering and tracking navigator (TT), tracking only navigator (TRON) techniques for image quality and focal liver lesions (FLL) detection in non-cirrhotic patients. Material and methods: This bi-centric study was approved by the institutional review boards; informed consent was obtained. Eighty-three patients were prospectively included and SE-EP-DWI with RT, TT and TRON techniques were performed. DWI sequences were randomized and independently analyzed by two readers. The qualitative evaluation was based on a 3-point score for axial artifacts (motion, ghost, susceptibility artifacts and distortion) and stair-step artifacts. Sensitivity of FLL detection was calculated for all lesions together and after lesion size stratification (≤10 mm, >10–20 mm and >20 mm). The standard of reference consisted of a retrospective reading of the conventional MRI, the three DWI sequences and by follow-up (12 months): a total of 409 FLL were detected. Data between sequences was compared with non-parametric tests. Cohen's kappa coefficient was used for inter-observer agreement. Results: Image quality was comparable for RT and TT. TRON showed statistically significantly more axial artifacts for the two readers ( p < 0.05). Stair-step artifacts were not statistically significantly different between DWI sequences. Overall sensitivities for RT, TT, TRON were 85%, 86%, 82% and 86%, 89% 83%, respectively, for readers 1 and 2. The inter-observer agreement was very good. Conclusion: Image quality was better for RT and TT compared to TRON. Overall sensitivities for FLL detection were comparable between techniques and readers.