Role of intestinal microbiota in transplantation outcomes. Issue 2 (June 2015)

• Record Type: Journal Article
• Authors: Taur, Ying; Jenq, Robert R.; Ubeda, Carles; van den Brink, Marcel; Pamer, Eric G.
• Is Part Of: Baillière's best practice and research in clinical haematology. Volume 28:Issue 2/3(2015)
• Page Start: 155
• Page End: 161
• Publication Date: 2015-06
• Subjects: Allo-HSCT -- Bacteremia -- Diversity -- Intestinal microbiota -- Microbial dominance -- Metronidazole -- Mortality -- Survival; allo-HSCT allogeneic HSCT -- HSCT hematopoietic stem cell transplantation -- VRE vancomycin-resistant Enterococcus; Hematology -- Periodicals; Blood -- Periodicals; Hematologic Diseases -- Periodicals; Electronic journals; 616
• DOI: 10.1016/j.beha.2015.10.013
• Languages: English
• ISSNs: 1521-6926

Abstract

Abstract: While allogeneic hematopoietic stem cell transplantations have a curative potential, infections and graft-versus-host disease remain significant problems. The intestinal microbiota can influence responses to cancer chemotherapy and the role of the microbiota in affecting allogeneic hematopoietic stem cell transplantation outcomes is increasingly appreciated. The following paper discusses the most recent developments in this area.