Isolation and characterization of antibiotic-resistant bacteria from pharmaceutical industrial wastewaters. (December 2015)

• Record Type: Journal Article
• Authors: Tahrani, Leyla; Soufi, Leila; Mehri, Ines; Najjari, Afef; Hassan, Abdenaceur; Van Loco, Joris; Reyns, Tim; Cherif, Ameur; Mansour, Hedi Ben
• Is Part Of: Microbial pathogenesis. Volume 89(2015)
• Page Start: 54
• Page End: 61
• Publication Date: 2015-12
• Subjects: Pharmaceutical effluent -- Antibiotic sensitivity -- Bacteria -- Multiple-drug resistance; Pathogenic microorganisms -- Periodicals; Pathology, Molecular -- Periodicals; Communicable Diseases -- microbiology -- Periodicals; Communicable Diseases -- parasitology -- Periodicals; Micro-organismes pathogènes -- Périodiques; Pathologie moléculaire -- Périodiques; Electronic journals; 616.9041
• DOI: 10.1016/j.micpath.2015.09.001
• Languages: English
• ISSNs: 0882-4010

Abstract

Abstract: Contamination of surface waters in underdeveloped countries is a great concern. Treated and untreated wastewaters have been discharged into rivers and streams, leading to possible waterborne infection outbreaks which may represent a significant dissemination mechanism of antibiotic resistance genes among pathogenic bacterial populations. The present study aims to determine the multi-drug resistance patterns among isolated and identified bacterial strains in a pharmaceutical wastewater effluent in north Tunisia. Fourteen isolates were obtained and seven of them were identified. These isolates belong to different genera namely, Pseudomonas, Acinetobacter, Exiguobacterium, Delftia and Morganella . Susceptibility patterns of these isolates were studied toward commonly used antibiotics in Tunisia. All the identified isolates were found to have 100% susceptibility against colistin sulfate and 100% resistance against amoxicillin. Among the 11 antibiotics tested, six patterns of multi-drug resistance were obtained. The potential of the examined wastewater effluent in spreading multi-drug resistance and the associated public health implications are discussed. Highlights: Significant dissemination mechanism of antibiotic resistance genes. Multi-drug resistance patterns among isolated and identified bacterial strains. Multiresistant bacteria in the public health deterioration.