Dietary glycemia as a determinant of health and longevity. (December 2015)

• Record Type: Journal Article
• Authors: Whitcomb, Elizabeth A.; Chiu, Chung-Jung; Taylor, Allen
• Is Part Of: Molecular aspects of medicine. Volume 46(2015)
• Page Start: 14
• Page End: 20
• Publication Date: 2015-12
• Subjects: Glycemic index -- Glycation -- Ubiquitin -- Proteasome -- Autophagy -- Eye disease; Pathology, Molecular -- Periodicals; Medicine -- Periodicals; Biochemistry -- Periodicals; Medicine -- Periodicals; Molecular Biology -- Periodicals; Pathologie moléculaire -- Périodiques; Médecine -- Périodiques; Electronic journals; 612.015
• DOI: 10.1016/j.mam.2015.08.005
• Languages: English
• ISSNs: 0098-2997

Abstract

Abstract: The role of diet in extending lifespan and healthspan has been the subject of much research and debate. Our recent epidemiological and in vivo data suggest that carbohydrate quality can be a major determinant in prolonging eye health. Additionally, excessive carbohydrate intake can contribute to the exacerbation of many different diseases. The metabolic diversity of the tissues that are affected by excessive carbohydrate intake suggests that dietary carbohydrate quality may affect cellular homeostasis.