Molybdenum hexacarbonyl mediated synthesis of indolin-2-one & azaindolin-2-one under catalyst free conditions. Issue 46 (18th November 2015)

• Record Type: Journal Article
• Authors: Patil, Vikas S.; Pal, Shyam S.; Pathare, Ramdas S.; Reddy, L.K.K.; Pathak, Arunendra
• Is Part Of: Tetrahedron letters. Volume 56:Issue 46(2015)
• Page Start: 6370
• Page End: 6372
• Publication Date: 2015-11-18
• Subjects: Azaindole -- Aminocarbonylation -- Oxindoles; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.09.123
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: Syntheses of indolin-2-ones and azaindolin-2-ones have been realized. The strategy involves the formation of tosylhydrazone from tosylhydrazine and 2-amino aryl or pyridyl aldehydes/ketones which then undergo intramolecular aminocarbonylation to afford indolin-2-ones and azaindolin-2-ones. The generality of the method was demonstrated by synthesizing C3 substituted and unsubstituted indolin-2-one and azaindolin-2-one derivatives.