Polydiacetylene liposome-encapsulated alginate hydrogel beads for Pb2+ detection with enhanced sensitivity. Issue 43 (30th September 2015)

• Record Type: Journal Article
• Authors: Wang, Dong-En; Wang, Yaolei; Tian, Chang; Zhang, Longlong; Han, Xiang; Tu, Qin; Yuan, Maosen; Chen, Sheng; Wang, Jinyi
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 43(2015)
• Page Start: 21690
• Page End: 21698
• Publication Date: 2015-09-30
• Subjects: Materials -- Research -- Periodicals; Chemistry, Analytic -- Periodicals; Environmental sciences -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c5ta04480d
• Languages: English
• ISSNs: 2050-7488

Abstract

Abstract : A new polydiacetylene liposome-based sensor was successfully constructed for the colorimetric and fluorometric detection of Pb 2+ . Abstract : The development of a novel and simple method to trace lead ions (Pb 2+ ) has received great attention due to its high toxicity to human health and the environment. In this paper, we describe a new polydiacetylene (PDA)-based liposome sensor for the colorimetric and fluorometric detection of Pb 2+ in aqueous solution and in alginate hydrogel microbeads. In the sensor system, a dopamine group was rationally introduced into a diacetylene monomer to work as a strong binding site for Pb 2+ . The dopamine-functionalized monomer and 10, 12-pentacosadiynoic acid (PCDA) were then incorporated into PDA liposomes in aqueous solution. After UV light-induced polymerization, deep blue colored liposome solutions were obtained. Upon the addition of various metal ions into the liposome solution, only Pb 2+ could cause a distinct color change from blue to red and a dramatic fluorescence enhancement. To further improve its sensitivity and address its intrinsic aggregation, we then developed a liposome-immobilized detection system by encapsulating PDA–DA liposomes into alginate hydrogel beads through a microfluidic droplet-based method. The results showed that the PDA–DA liposome-containing hybrid hydrogel beads possessed excellent stability and high sensitivity. These interesting findings demonstrated that the PDA liposome system developed in the current study may offer a new method for Pb 2+ recognition in a more efficient manner.