Dual T1/T2 MRI contrast agent based on hybrid SPION@coordination polymer nanoparticles. Issue 105 (13th October 2015) - Borges, M.
Abstract : A novel dual T 1 / T 2 1 H-MRI contrast agent based on the encapsulation of super-paramagnetic iron oxide nanoparticles (SPIONs) with an iron coordination polymer is proposed. Abstract : We report a novel hybrid T 1 / T 2 dual MRI contrast agent by the encapsulation of SPIONs ( T 2 contrast agent) into an iron-based coordination polymer with T 1 -weighted signal. This new hybrid material presents improved relaxometry and low cytotoxicity, which make it suitable for its use as contrast agent for MRI.