Silver-catalysed reactions of alkynes: recent advances. (29th July 2015)

• Record Type: Journal Article
• Authors: Fang, Guichun; Bi, Xihe
• Is Part Of: Chemical Society reviews. Volume 44:Number 22(2015:Nov.)
• Page Start: 8124
• Page End: 8173
• Publication Date: 2015-07-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cs00027k
• Languages: English
• ISSNs: 0306-0012

Abstract

Abstract : Silver is a less expensive noble metal. Superior alkynophilicity due to π-coordination with the carbon–carbon triple bond makes silver salts ideal catalysts for alkyne-based organic reactions. This critical review clearly indicates that alkyne chemistry has been greatly benefiting from the emerging " Silver Rush " and will continue to generate increasingly more synthetic possibilities in the near future. Abstract : Silver is a less expensive noble metal. Superior alkynophilicity due to π-coordination with the carbon–carbon triple bond makes silver salts ideal catalysts for alkyne-based organic reactions. This review highlights the progress in alkyne chemistry via silver catalysis primarily over the past five years ( ca. 2010–2014). The discussion is developed in terms of the bond type formed with the acetylenic carbon ( i.e., C–C, C–N, C–O, C–Halo, C–P and C–B). Compared with other coinage metals such as Au and Cu, silver catalysis is frequently observed to be unique. This critical review clearly indicates that silver catalysis provides a significant impetus to the rapid evolution of alkyne-based organic reactions, such as alkynylation, hydrofunctionalization, cycloaddition, cycloisomerization, and cascade reactions.