Synthesis of novel polymerizable molecules bearing bisphosphonate. Issue 46 (7th October 2015)

• Record Type: Journal Article
• Authors: Kachbi Khelfallah, S.; Monteil, M.; Deschamp, J.; Gager, O.; Migianu-Griffoni, E.; Lecouvey, M.
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 46(2015)
• Page Start: 11382
• Page End: 11392
• Publication Date: 2015-10-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob01967b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : In recent years, bisphosphonate chemistry has undergone an exponential growth due to the potential applications of these compounds in medicine and nanobiomaterial research. Abstract : In recent years, bisphosphonate chemistry has undergone an exponential growth due to the potential applications of these compounds in medicine and nanobiomaterial research. In this paper we describe the synthesis methods of different families of methacrylic monomers bearing a bisphosphonate with varying lengths of the chain, PEG linkers and more or less hydrolysable functions such as ester, carbamate or amide.