Inside Cover: Catalytic Molecular Imaging of MicroRNA in Living Cells by DNA‐Programmed Nanoparticle Disassembly (Angew. Chem. Int. Ed. 9/2016). Issue 9 (28th January 2016)

• Record Type: Journal Article
• Authors: He, Xuewen; Zeng, Tao; Li, Zhi; Wang, Ganglin; Ma, Nan
• Is Part Of: Angewandte Chemie international edition. Volume 55:Issue 9(2016)
• Page Start: 2948
• Page End: 2948
• Publication Date: 2016-01-28
• Subjects: catalysis -- gold nanoparticles -- microRNAs -- molecular imaging -- quantum dots; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201600456
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : The sensitive imaging of microRNA in living cells remains challenging because of their low abundance. In their Communication onpage 3073 ff., N. Ma and co‐workers demonstrate that microRNA can serve as a catalyst to trigger the disassembly of quantum dots (QDs) and gold nanoparticles with multiple turnovers, which yields significantly amplified QD photoluminescence for microRNA imaging in living cells.