Synthesis of Strained γ‐Lactams by Palladium(0)‐Catalyzed C(sp3)−H Alkenylation and Application to Alkaloid Synthesis. (21st January 2016)
- Record Type:
- Journal Article
- Title:
- Synthesis of Strained γ‐Lactams by Palladium(0)‐Catalyzed C(sp3)−H Alkenylation and Application to Alkaloid Synthesis. (21st January 2016)
- Main Title:
- Synthesis of Strained γ‐Lactams by Palladium(0)‐Catalyzed C(sp3)−H Alkenylation and Application to Alkaloid Synthesis
- Authors:
- Holstein, Philipp M.
Dailler, David
Vantourout, Julien
Shaya, Janah
Millet, Anthony
Baudoin, Olivier - Abstract:
- Abstract: A variety of strained α‐alkylidene‐γ‐lactams were synthesized by palladium(0)‐catalyzed intramolecular C(sp 3 )−H alkenylation from easily accessible acyclic and monocyclic bromoalkene precursors. These lactams are valuable intermediates for accessing various classes of mono‐ and bicylic alkaloids containing a pyrrolidine ring, as illustrated with the synthesis of an advanced model of the marine natural product plakoridine A and of the indolizidine alkaloid δ‐coniceine.
- Is Part Of:
- Angewandte Chemie. Volume 128:Number 8(2016)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 128:Number 8(2016)
- Issue Display:
- Volume 128, Issue 8 (2016)
- Year:
- 2016
- Volume:
- 128
- Issue:
- 8
- Issue Sort Value:
- 2016-0128-0008-0000
- Page Start:
- 2855
- Page End:
- 2859
- Publication Date:
- 2016-01-21
- Subjects:
- C-C-Kupplung -- C-H-Aktivierung -- Naturstoffe -- Palladium -- Stickstoffheterocyclen
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201511457 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 1248.xml