Dual metal and Lewis base catalysis approach for asymmetric synthesis of dihydroquinolines and the α-arylation of aldehydes via N-acyliminium ions. Issue 87 (14th September 2015)

• Record Type: Journal Article
• Authors: Volla, Chandra M. R.; Fava, Eleonora; Atodiresei, Iuliana; Rueping, Magnus
• Is Part Of: Chemical communications. Volume 51:Issue 87(2015)
• Page Start: 15788
• Page End: 15791
• Publication Date: 2015-09-14
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc05209b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A dual catalytic system consisting of indium triflate and a chiral imidazolidinone catalyzes the asymmetric addition of aldehydes to N -acyl quinoliniums furnishing optically active dihydroquinolines in good yields and excellent selectivities. Abstract : A dual catalytic system consisting of indium triflate and a chiral imidazolidinone catalyzes the asymmetric addition of aldehydes to N -acyl quinoliniums furnishing optically active dihydroquinolines in good yields and excellent selectivities. The products were further functionalized into optically active tetrahydroquinolines, quinolines and 6-oxa-2-aza-bicyclo[3.3.1]nonanes.