Combinatorial Biomolecular Nanopatterning for High‐Throughput Screening of Stem‐Cell Behavior. Issue 7 (9th December 2015)

• Record Type: Journal Article
• Authors: Amin, Yacoub Y. I.; Runager, Kasper; Simoes, Fabio; Celiz, Adam; Taresco, Vincenzo; Rossi, Roberto; Enghild, Jan J.; Abildtrup, Lisbeth A.; Kraft, David C. E.; Sutherland, Duncan S.; Alexander, Morgan R.; Foss, Morten; Ogaki, Ryosuke
• Is Part Of: Advanced materials. Volume 28:Issue 7(2016)
• Page Start: 1472
• Page End: 1476
• Publication Date: 2015-12-09
• Subjects: cell adhesion -- combinatorial -- high throughput -- nanofabrication -- protein patterning; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201504995
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : A novel combinatorial biomolecular nanopatterning method is reported, in which multiple biomolecular ligands can be patterned in multiple nanoscale dimensions on a single surface. The applicability of the combinatorial platform toward cell‐biology applications is demonstrated by screening the adhesion behavior of a population of human dental pulp stem cell (hDPSC) on 64 combinations of nanopatterned extracellular matrix (ECM) proteins in parallel.