Comparing Abbott m2000 RealTime HIV test and Roche COBAS Ampliprep/COBAS Taqman HIV test, v2.0 in treated HIV‐1 B and non‐B subjects with low viraemia. Issue 4 (21st September 2015)

• Record Type: Journal Article
• Authors: Margariti, Apostolia; Chatzidimitriou, Dimitrios; Metallidis, Simeon; Pilalas, Dimitrios; Kourelis, Andreas; Papadimitriou, Evangelia; Haidich, Anna‐Bettina; Malisiovas, Nicolaos; Skoura, Lemonia
• Is Part Of: Journal of medical virology. Volume 88:Issue 4(2016)
• Page Start: 724
• Page End: 727
• Publication Date: 2015-09-21
• Subjects: viral load -- real time PCR -- HIV subtype -- agreement study; Virology -- Periodicals; 616
• DOI: 10.1002/jmv.24369
• Languages: English
• ISSNs: 0146-6615

Abstract

Abstract : Viral load testing is a valuable tool in HIV clinical care and research. Discrepancies among diverse viral load assays, especially with regard to non‐B HIV‐1 subtypes have been reported. Our study aimed to explore the impact of HIV subtype (B versus non‐B) on the agreement between CAP/CTM, v2.0 and m2000 RealTime in treated HIV patients, focusing on low viral loads (<200 copies/ml). Our findings indicate that there is a significant difference in the performance of the compared assays in the low‐viremic range and non–B subtypes, suggesting that a single assay should be used for follow‐up. J. Med. Virol. 88:724–727, 2016 . © 2015 Wiley Periodicals, Inc.