A green and sustainable phosphine-free NHC-ruthenium catalyst for selective oxidation of alcohols to carboxylic acids in water. Issue 39 (21st September 2015)

• Record Type: Journal Article
• Authors: Malineni, Jagadeesh; Keul, Helmut; Möller, Martin
• Is Part Of: Dalton transactions. Volume 44:Issue 39(2015)
• Page Start: 17409
• Page End: 17414
• Publication Date: 2015-09-21
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c5dt01358e
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : An efficient novel protocol is applied for direct synthesis of carboxylic acids from primary alcohols through catalytic dehydrogenation. This reaction occurs in water as the solvent and as the oxygen-atom source and no toxic oxidizing agent is involved. Abstract : In this work, we present a new catalytic system for the selective dehydrogenative oxidation of primary alcohols to carboxylic acids using a phosphine-free NHC-ruthenium catalyst in water under mild reaction conditions. With this catalytic system, a variety of primary alcohols have been converted to carboxylic acids respectively, in aqueous media, without using any additional oxidant; the only side product in this reaction is molecular hydrogen. This novel synthetic protocol is applied for direct oxidation of biologically active monosaccharides and polymers with primary alcohol groups in the side chain. The use of water as a solvent and oxygen donor as well as the absence of any toxic oxidizing agent make this atom economical reaction interesting from an environmental point of view.