Spontaneous laterality in mouse Crl:CD1. Issue 1 (2nd January 2016)

• Record Type: Journal Article
• Authors: Maciejewska, Maria; Zięba, Katarzyna; Szymańska, Justyna; Warońska, Magdalena
• Is Part Of: Laterality. Volume 21:Issue 1(2016)
• Page Start: 76
• Page End: 84
• Publication Date: 2016-01-02
• Subjects: Lateralization -- spontaneous laterality -- mouse -- mouse Crl:CD1 -- T-shaped maze; Laterality -- Periodicals; Cerebral dominance -- Periodicals; 616.8
• DOI: 10.1080/1357650X.2015.1075024
• Languages: English
• ISSNs: 1357-650X

Abstract

ABSTRACT: Lateralization developed very early in evolution and it is a characteristic of a wide range of representatives from the animal kingdom. The aim of the present study was to examine the spontaneous laterality in mice ( Mus musculus ) with the T-maze test. We wanted to check if this kind of functional asymmetry occurs at a population level, and also if there are gender differences in this regard. The study involved 40 mice Crl:CD1. The research procedure was simple: mice had to choose one arm of the T-shaped apparatus to find the exit. The animals performed the 10 trails one after another. We took into account only the animals' fist reactions while preparing results. Most of the animals (68%) chose the right arm of the maze. The lateralization was stronger among females—75% of them had preferences for the right side. The majority of animals, which preferred the right side, were from the food deprivation group. However, the results did not unequivocally resolve whether mice evince the functional asymmetry at the population level, or whether there are gender differences in this area. Further research with a larger group and multiple observations for each animal are required to answer these questions.