Facile Synthesis of Functionalized Carbene Metal Complexes from Coordinated Isonitriles. Issue 3 (3rd July 2015)

• Record Type: Journal Article
• Authors: Lothschütz, Christian; Wurm, Thomas; Zeiler, Anna; Freiherr v. Falkenhausen, Alexander; Rudolph, Matthias; Rominger, Frank; Hashmi, A. Stephen K.
• Is Part Of: Chemistry, an Asian journal. Volume 11:Issue 3(2016)
• Page Start: 342
• Page End: 346
• Publication Date: 2015-07-03
• Subjects: amines -- gold -- isonitriles -- Michael acceptors -- phosphonates; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201500353
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract: The scope and limitations of the isonitrile‐based NHC template synthesis were investigated with a series of precursors containing a nucleophilic amine in combination with tethered electrophiles. In the case of alkynes and phosphonic esters as electrophiles no ring closure was observed and new functionalized NAC gold complexes were obtained. By the use of unsaturated esters and phosphonic esters as Michael acceptors in the amine precursors, ester‐modified gold and palladium NHC complexes were accessible in high efficiency. Abstract : Functionalized carbene metal complexes can be obtained in an easy and modular approach following the isonitrile route. Functional groups that are not tolerated by classical NHC syntheses can be applied with metal‐coordinated isonitriles. The obtained ester‐ and phosphonic ester modified Au and Pd complexes are potential precursors for further derivations.