A new sesquiterpene from the entomogenous fungus Phomopsis amygdali. Issue 3 (1st February 2016)

• Record Type: Journal Article
• Authors: Ma, Xiaoli; Wang, Wenshu; Li, Erwei; Gao, Fenghua; Guo, Liangdong; Pei, Yunfei
• Is Part Of: Natural product research. Volume 30:Issue 3(2016)
• Page Start: 276
• Page End: 280
• Publication Date: 2016-02-01
• Subjects: entomogenous fungus -- Phomopsis amygdali -- (+)-S-1-methyl-abscisic-6-acid -- antimicrobial activity -- Pseudomonas aeruginosa 2033; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1055742
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract : A new sesquiterpene, (+)- S -1-methyl-abscisic-6-acid (1 ), together with five known compounds, (+)- S -abscisic acid (2 ), fusicoccin J (3 ), 3α-hydroxyfusicoccin J (4 ), ( R )-5-hydroxymethylmellein (5 ) and 4-hydroxyphenethyl acetate (6 ) was isolated from the fermentation extract of Phomopsis amygdali, an entomogenous fungus isolated from Call midge . Their structures were determined mainly by analysis of MS and NMR spectroscopic data. Compounds1 –6 were tested for antimicrobial activity against three plant pathogenic fungi: Gibberella zeae, Verticillium albo-atrum, and Fusarium nivale, and two bacteria: Escherichia coli and Pseudomonas aeruginosa 2033E. As a result, compounds1 –4 displayed antibacterial activity against Gram-negative P. aeruginosa 2033E, and the minimum inhibition concentration (MIC value) of1 –4 is 30 μg/mL, 58 μg/mL, 26 μg/mL, and 26 μg/mL, respectively. Abstract :