A new sesquiterpenoid quinone with cytotoxicity from Abelmoschus sagittifolius. Issue 5 (3rd March 2016)

• Record Type: Journal Article
• Authors: Chen, De-Li; Zhang, Xiao-Po; Ma, Guo-Xu; Wu, Hai-Feng; Yang, Jun-Shan; Xu, Xu-Dong
• Is Part Of: Natural product research. Volume 30:Issue 5(2016)
• Page Start: 565
• Page End: 569
• Publication Date: 2016-03-03
• Subjects: Abelmoschus sagittifolius -- sesquiterpenoid -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1033624
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract : A new sesquiterpenoid quinone, Acyl hibiscone B (1 ), together with five known compounds, ( R )-lasiodiplodin (2 ), ( R )-de- O -methyllasiodiplodin, (3 ) dibutyl phthalate (4 ), ( R )-9-phenylnonan-2-ol (5 ) and hibiscone B (6 ), was obtained from the stem tuber of Abelmoschus sagittifolius . The structure of compound1 was elucidated by analysing its 1 H and 13 C NMR, 1 H– 1 H COSY, HSQC, HMBC, NOESY and HR-ESI-MS values. Compound1 showed significant cytotoxicity against Hela and HepG-2 human cancer cell lines. Abstract :