Possible esthesioneuroblastoma metastasis to paranasal sinuses: Clinical report and literature review. Issue 2 (14th July 2015)

• Record Type: Journal Article
• Authors: Buohliqa, Lamia; Upadhyay, Smita; Nicolai, Piero; Cavalieri, Robert; Dolci, Ricardo L. L.; Prevedello, Daniel; Carrau, Ricardo L.
• Is Part Of: Head & neck. Volume 38:Issue 2(2016)
• Page Start: E32
• Page End: E36
• Publication Date: 2015-07-14
• Subjects: endoscopic endonasal approach -- esthesioneuroblastoma -- skull base surgery -- ectopic tumor -- recurrence; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.24095
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Background: Local recurrence, and regional and distant metastases, respectively, develop in 30% and 15% of patients with esthesioneuroblastoma (ENB). Methods: This case report includes 3 patients with unusual recurrences of ENB in the sinonasal tract. Results: Patient 1 developed ENB in the bilateral maxillary sinuses after unilateral endoscopic resection of a left ENB followed by postoperative proton radiotherapy. Patient 2 developed ENB at the left optic‐carotid recess 7 years after a craniofacial resection and postoperative radiotherapy. Patient 3 developed ENB over the left zygomatic process of the maxilla 4 years after a cranioendoscopic resection and postoperative radiation therapy for ENB of the ethmoid sinuses with intracranial extension. The possibility of venous tumor emboli must be considered as a likely etiology. However, alternative explanations include the development of a second primary or potential transformation because of tumor signaling. Conclusion: We present 3 cases that may represent metastasis of ENB within the sinonasal tract. © 2015 Wiley Periodicals, Inc. Head Neck 38: E32–E36, 2016