Polycaprolactone-based biomaterials for tissue engineering and drug delivery: Current scenario and challenges. Issue 5 (23rd March 2016)

• Record Type: Journal Article
• Authors: Mondal, Debasish; Griffith, May; Venkatraman, Subbu S.
• Is Part Of: International journal of polymeric materials. Volume 65:Issue 5(2016)
• Page Start: 255
• Page End: 265
• Publication Date: 2016-03-23
• Subjects: Biomaterial -- drug delivery -- polycaprolactone -- scaffold -- tissue engineering; Polymers -- Periodicals; Plastics -- Periodicals; 620.19205
• DOI: 10.1080/00914037.2015.1103241
• Languages: English
• ISSNs: 0091-4037

Abstract

ABSTRACT: Recently, poly (є-caprolactone) (PCL) has gained a lot of attention, and shown great potential in biomedical applications. Among synthetic polymers, PCL is one of the easiest to process and manipulate into a large range of shapes and sizes due to its low melting temperature and its superior viscoelastic properties. In this review article the authors focus mainly on the properties of PCL-based biomaterials relevant to drug delivery and tissue engineering applications. The authors provide an insight into the recent developments and challenges of PCL-based biomaterials as a critical component of new therapeutic strategies for many diseases. GRAPHICAL ABSTRACT: