ChemInform Abstract: One‐Step Synthesis of 2‐Chloropyrimidin‐4‐ol Derivatives: An Unusual Reactivity of Thiophosgene. Issue 8 (February 2016)

• Record Type: Journal Article
• Authors: Callingham, Michael; Blum, Francesca; Pave, Gregoire
• Is Part Of: ChemInform. Volume 47:Issue 8(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-02
• Subjects: fused pyrimidine derivatives -- ring closure reactions, annulation reactions; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201608185
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The reaction of 2‐aminobenzamides (IV) with thiophosgene leads to 2‐chloropyrimidin‐4‐ol derivatives, which are converted without purification into 2‐morpholine derivatives (VI).