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ChemInform Abstract: Synthesis of Virtually Enantiopure Aminodiols with Three Adjacent Stereogenic Centers by Epoxidation and Ring‐Opening. Issue 8 (February 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Synthesis of Virtually Enantiopure Aminodiols with Three Adjacent Stereogenic Centers by Epoxidation and Ring‐Opening. Issue 8 (February 2016)
Main Title:
ChemInform Abstract: Synthesis of Virtually Enantiopure Aminodiols with Three Adjacent Stereogenic Centers by Epoxidation and Ring‐Opening.
Abstract: A virtually complete enantioselective synthesis of 3‐amino‐1, 2‐diols, e.g. (IV) and (VII), is accomplished by a sequential cascade of two kinetic resolutions, which features a Sharpless or Hafnium‐catalyzed asymmetric epoxidation, and a subsequent tungsten‐catalyzed aminolysis.