Translational research on Barrett's esophagus. (29th September 2014)

• Record Type: Journal Article
• Authors: Baruah, Anushka; Buttar, Navtej; Chandra, Raghav; Chen, Xiaoxin; Clemons, Nicholas J.; Compare, Debora; El‐Rifai, Wael; Gu, Jian; Houchen, Courtney W.; Koh, Shze Yung; Li, Wenbo; Nardone, Gerardo; Phillips, Wayne A.; Sharma, Anamay; Singh, Ishtpreet; Upton, Melissa P.; Vega, Kenneth J.; Wu, Xifeng
• Is Part Of: Annals of the New York Academy of Sciences. Volume 1325(2014)
• Page Start: 170
• Page End: 186
• Publication Date: 2014-09-29
• Subjects: Barrett's esophagus -- microsatellite instability -- DCLK -- oxidative stress -- modeling -- esophageal adenocarcinoma -- OESO; Medical sciences -- Periodicals; Medicine -- Periodicals; Science -- Periodicals; 610
• DOI: 10.1111/nyas.12531
• Languages: English
• ISSNs: 0077-8923

Abstract

Abstract : The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on translational research on Barrett's esophagus that address evidence for genetic instability in esophageal cancer; the role of microsatellite instability; the use of histologic and serum Doublecortin‐like kinase 1 expression for progression of Barrett's esophagus to adenocarcinoma; the oxidative stress in Barrett's tumorigenesis; the genomic alterations in esophageal cancer; in vivo modeling in Barrett's esophagus; epigenetic and transcriptional regulation in Barrett's esophagus and esophageal adenocarcinoma; and normal and disordered regeneration in Barrett's esophagus.