ChemInform Abstract: Novel Synthesis and Cytotoxic Activity of 1, 4‐Disubstituted 3‐Methylidene‐3, 4‐dihydroquinolin‐2(1H)‐ones. Issue 6 (21st January 2016)

• Record Type: Journal Article
• Authors: Pieta, Marlena; Kedzia, Jacek; Janecka, Anna; Pomorska, Dorota K.; Rozalski, Marek; Krajewska, Urszula; Janecki, Tomasz
• Is Part Of: ChemInform. Volume 47:Issue 6(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-01-21
• Subjects: quinoline derivatives -- C‐C bond formation -- reactions of organo‐metal compounds -- anticarcinogenic activity, anticancer activity; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201606181
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The title compounds are prepared in a 3‐step sequence starting from (I) via N‐alkylation, Grignard addition and Horner‐Wadsworth‐Emmons reaction with formaldehyde.