From corneal shape to ocular wavefront in eyes with aspheric IOLs: the feasibility of IOL customisation. (21st October 2015)

• Record Type: Journal Article
• Authors: de Jong, Tim; Canovas, Carmen; Weeber, Henk; Jansonius, Nomdo M.
• Is Part Of: Ophthalmic and physiological optics. Volume 36:Number 1(2016:Jan.)
• Page Start: 43
• Page End: 50
• Publication Date: 2015-10-21
• Subjects: aspheric IOL -- cataract -- corneal wavefront aberration -- IOL customisation -- ocular wavefront; Ophthalmology -- Periodicals; Physiological optics -- Periodicals; Optometry -- Periodicals; Optics -- Periodicals; Vision -- Periodicals; 617.75
• DOI: 10.1111/opo.12258
• Languages: English
• ISSNs: 0275-5408

Abstract

Abstract: Purpose: To determine if it is possible to predict the ocular wavefront aberrations of eyes with an aspheric IOL from the corneal shape and other readily available eye characteristics. A reliable prediction is a prerequisite for future IOL customisation. Methods: Sixty pseudophakic eyes with aspheric IOLs of 60 patients were included. The corneal shape and the ocular wavefront aberrations were measured postoperatively with a Scheimpflug camera and an aberrometer, respectively. The elevation data of the anterior corneal surface were fitted by Zernike polynomials. Linear regression models for the Zernike coefficients describing the ocular wavefront aberrations up till the fourth order were determined, with as independent variables the Zernike coefficients describing the corneal shape, the eye (right/left), IOL power, and axial length. Results: Linear regression equations with an explained variance (adjusted R ‐square) above 0.50 were found for five Zernike aberration terms: defocus ( z (2, 0); adjusted R ‐square 0.90), the astigmatism terms (0.81 for oblique astigmatism [ z (2, −2)] and 0.88 for regular astigmatism [ z (2, 2)]), vertical coma ( z (3, −1); 0.52), and spherical aberration ( z (4, 0); 0.71). Conclusion: The defocus, astigmatism, vertical coma, and spherical aberration terms of the ocular wavefront are strongly associated with the corneal shape in pseudophakic eyes and may thus be predicted from the corneal shape and other eye characteristics.