Inside Cover: Light‐Controlled Cellular Internalization and Cytotoxicity of Nucleic Acid‐Binding Agents: Studies in Vitro and in Zebrafish Embryos (ChemBioChem 1/2016). Issue 1 (5th January 2016) - Penas, Cristina
Abstract : The inside cover picture shows a short oligoglutamic peptide as a ball and chain that does not allow a DNA‐binding conjugate (octaarginine–small molecule hybrid) to internalize and/or bind nucleic acids. Irradiation releases the inactivating chain and thus triggers the cell entry and nucleic acid binding abilities of the conjugate. More information can be found in the communication by E. Vázquez, J. L. Mascareñas, et al. onpage 37 in Issue 1, 2016 (DOI:10.1002/cbic.201500455 ).