NIR‐Remote Selected Activation Gene Expression in Living Cells by Upconverting Microrods. Issue 4 (30th November 2015)

• Record Type: Journal Article
• Authors: Zheng, Bin; Su, Lin; Pan, Huizhuo; Hou, Beibei; Zhang, Ying; Zhou, Fang; Wu, Xiaoli; Gong, Xiaoqun; Wang, Hanjie; Chang, Jin
• Is Part Of: Advanced materials. Volume 28:Issue 4(2016)
• Page Start: 707
• Page End: 714
• Publication Date: 2015-11-30
• Subjects: upconverting rods -- light‐sensitive molecules -- NIR‐remote selected activation -- gene expression -- photosensitivity; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201503961
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : An NIR‐controlled gene expression system based on upconverting rods (UCRs) is demonstrated. The UCRs can harvest the "biocompatible" NIR light and convert it into local UV light, resulting in cleavage of the photosensitive molecule (4‐(hydroxymethyl)‐3‐nitrobenzoic acid, ONA) and on‐demand release of gene carriers, thus realizing target gene expression at high spatial and temporal resolutions.