Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia. Issue 1 (1st December 2015)

• Record Type: Journal Article
• Authors: Whyte, Martin; Quaglia, Alberto; Hopkins, David
• Is Part Of: Clinical case reports. Volume 4:Issue 1(2016)
• Page Start: 83
• Page End: 86
• Publication Date: 2015-12-01
• Subjects: detemir -- hepatoselective -- NAFLD -- hypertriglyceridaemia; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.458
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin. Abstract : Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.