Practical guide to sample size calculations: an introduction. (20th November 2015)

• Record Type: Journal Article
• Authors: Flight, Laura; Julious, Steven A.
• Is Part Of: Pharmaceutical statistics. Volume 15:Number 1(2016)
• Page Start: 68
• Page End: 74
• Publication Date: 2015-11-20
• Subjects: sample size -- superiority -- non‐inferiority -- equivalence -- power -- clinical trials; Pharmacy -- Statistical methods -- Periodicals; Pharmacy -- Statistics -- Periodicals; 615.10727
• DOI: 10.1002/pst.1709
• Languages: English
• ISSNs: 1539-1604

Abstract

Abstract : A sample size justification is a vital step when designing any trial. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the general steps are summarised for conducting sample size calculations with practical advice and guidance on how to utilise the app SampSize. Copyright © 2015 John Wiley & Sons, Ltd.