Submicrometer‐Sized Thermometer Particles Exploiting Selective Nucleic Acid Stability. Issue 4 (15th December 2015)

• Record Type: Journal Article
• Authors: Puddu, Michela; Mikutis, Gediminas; Stark, Wendelin J.; Grass, Robert N.
• Is Part Of: Small. Volume 12:Issue 4(2016)
• Page Start: 452
• Page End: 456
• Publication Date: 2015-12-15
• Subjects: deoxyribonucleic acid -- polymerase chain reactions -- ribonucleic acid -- nucleic acids -- silica -- temperature; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201502883
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : Encapsulated nucleic acid selective damage quantification by real‐time polymerase chain reaction is used as sensing mechanism to build a novel class of submicrometer size thermometer. Thanks to the high thermal and chemical stability, and the capability of storing the read accumulated thermal history, the sensor overcomes some of current limitations in small scale thermometry.