Cancer Treatment: Medibots: Dual‐Action Biogenic Microdaggers for Single‐Cell Surgery and Drug Release (Adv. Mater. 5/2016). Issue 5 (February 2016)

• Record Type: Journal Article
• Authors: Srivastava, Sarvesh Kumar; Medina‐Sánchez, Mariana; Koch, Britta; Schmidt, Oliver G.
• Is Part Of: Advanced materials. Volume 28:Issue 5(2016)
• Page Start: 785
• Page End: 785
• Publication Date: 2016-02
• Subjects: biogenic micromotors -- cancer treatments -- drug delivery -- microdrilling -- non‐invasive microsurgery; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201670029
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : On page 832, S. K. Srivastava and co‐workers present dual‐action biogenic microbots with a dagger‐like morphology for cellular microsurgery and drug delivery. These biocompatible micromotors allow magnetically controlled drilling into a target cell (red) along with the sustained release of a loaded drug (e.g., pH‐triggered anticancer drugs). This study highlights "selective targeting and destruction" of harmful cells in living systems and advances the understanding of microscale interactions at the cellular level.