Diffraction tomography and Rietveld refinement of a hydroxyapatite bone phantom. (21st January 2016)

• Record Type: Journal Article
• Authors: Frølich, S.; Leemreize, H.; Jakus, A.; Xiao, X.; Shah, R.; Birkedal, H.; Almer, J. D.; Stock, S. R.
• Is Part Of: Journal of applied crystallography. Volume 49:Part 1(2016:Feb.)
• Page Start: 103
• Page End: 109
• Publication Date: 2016-01-21
• Subjects: X‐ray diffraction tomography -- Rietveld refinement -- hydroxyapatite -- bone; Crystallography -- Periodicals; 548.05
• DOI: 10.1107/S1600576715022633
• Languages: English
• ISSNs: 0021-8898

Abstract

Abstract : High‐energy X‐ray diffraction tomography and Rietveld refinement were used to reconstruct the quantitative differences between hydroxyapatite powders in a bone phantom. Abstract : A model sample consisting of two different hydroxyapatite (hAp) powders was used as a bone phantom to investigate the extent to which X‐ray diffraction tomography could map differences in hAp lattice constants and crystallite size. The diffraction data were collected at beamline 1‐ID, the Advanced Photon Source, using monochromatic 65 keV X‐radiation, a 25 × 25 µm pinhole beam and translation/rotation data collection. The diffraction pattern was reconstructed for each volume element (voxel) in the sample, and Rietveld refinement was used to determine the hAp lattice constants. The crystallite size for each voxel was also determined from the 00.2 hAp diffraction peak width. The results clearly show that differences between hAp powders could be measured with diffraction tomography.