Vagus Nerve Stimulator Placement in Dogs: Surgical Implantation Technique, Complications, Long‐Term Follow‐Up, and Practical Considerations. Issue 1 (January 2016)

• Record Type: Journal Article
• Authors: Martlé, Valentine; Van Ham, Luc M. L.; Boon, Paul; Caemaert, Jacques; Tshamala, Mulenda; Vonck, Kristl; Raedt, Robrecht; Polis, Ingeborgh; Bhatti, Sofie
• Is Part Of: Veterinary surgery. Volume 45:Issue 1(2016)
• Page Start: 71
• Page End: 78
• Publication Date: 2016-01
• Subjects: Veterinary surgery -- Periodicals; Veterinary Medicine -- Periodicals; Surgery -- Periodicals; Societies, Medical -- Periodicals; 636.0897
• DOI: 10.1111/vsu.12427
• Languages: English
• ISSNs: 0161-3499

Abstract

Abstract : Objective: To describe a modified implantation procedure of a vagus nerve stimulation (VNS) device in dogs and to report short‐ and long‐term complications. Study Design: Descriptive, experimental study. Animals: Healthy, adult Beagle dogs (n = 10). Methods: A VNS Therapy ® System was implanted in the left cervical region of anesthetized dogs. During and within 48 hours after surgery, electrocardiography (ECG) and impedance testing of the system were performed. Dogs were monitored daily and the impedance of the system was determined regularly until VNS devices were surgically removed 3 years after implantation. Results: The implantation procedure was successful in all dogs without intraoperative complications. ECG monitoring and impedance tests were within normal limits during and within 48 hours after surgery. Postoperative seroma formation was common (70%). One dog developed an irreversible Horner's syndrome leading to removal of the device 5 months after implantation. Another dog developed trauma‐induced damage of the lead requiring surgical revision. The device could be safely removed in all dogs; however, electrodes were left in place to avoid nerve damage. At removal, the anchor tether was dislodged in 40% of dogs and the lead was twisted in 50% of dogs. Conclusion: Implantation of a VNS Therapy ® System is safe and feasible in dogs; however, seroma formation, twisting of the lead, and dislodgement of the anchor tether were common. Practical improvements in the technique include stable device placement, use of a compression bandage, and exercise restriction. Regular evaluation of lead impedance is important, as altered values can indicate serious complications.