Immune Reconstitution Inflammatory Syndrome Secondary to Mycobacterium kansasii Infection in a Kidney Transplant Recipient. Issue 12 (15th September 2015)

• Record Type: Journal Article
• Authors: Lemoine, M.; Laurent, C.; Hanoy, M.; Leporrier, J.; François, A.; Guerrot, D.; Godin, M.; Bertrand, D.
• Is Part Of: American journal of transplantation. Volume 15:Issue 12(2015:Dec.)
• Page Start: 3255
• Page End: 3258
• Publication Date: 2015-09-15
• Subjects: clinical research / practice -- kidney transplantation / nephrology -- infectious disease -- antibiotic: antibacterial -- complication: infectious -- immunosuppressive regimens -- infection -- mycobacterial: nontuberculous -- kidney (allograft) function / dysfunction; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.13433
• Languages: English
• ISSNs: 1600-6135

Abstract

Abstract : Nontuberculous mycobacteria (NTM) infection is a challenging diagnosis for clinicians in solid organ transplantation. Immune reconstitution inflammatory syndrome (IRIS) is so far unreported in this context. We report here the case of a renal transplant recipient who developed Mycobacterium kansasii –associated lymphadenitis complicated by IRIS while undergoing reduction of his immunosuppressive therapy. For IRIS, the patient required low‐dose steroids and an increase in global immunosuppression, in association with NTM antibiotherapy. Abstract : The authors report an original case of immune reconstitution inflammatory syndrome secondary to Mycobacterium kansasii lymphadenitis in a kidney transplant patient, highlighting the importance of its recognition to manage an immunosuppression regimen.