ChemInform Abstract: An Asymmetric Organocatalytic Quadruple Domino Reaction Employing a Vinylogous Friedel—Crafts/Michael/Michael/Aldol Condensation Sequence. Issue 52 (10th December 2015)

• Record Type: Journal Article
• Authors: Philipps, Arne R.; Fritze, Lars; Erdmann, Nico; Enders, Dieter
• Is Part Of: ChemInform. Volume 46:Issue 52(2015)
• Page Start: no
• Page End: no
• Publication Date: 2015-12-10
• Subjects: polyphenylalkane derivatives -- ring closure reactions, annulation reactions -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- multicomponent reactions -- cascade reactions, domino reactions, tandem reactions -- organocatalysis; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201552082
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: Highly functionalized cyclohexenecarbaldehydes bearing a 1, 1‐bis[4‐(dialkylamino)phenyl]ethene moiety and three contiguous stereogenic centers are synthesized with very good diastereoselectivity, virtually complete enantiomeric excess, and good functional group tolerance.