Efficient and facile synthesis of novel stable monodeuterium labeled ractopamine. (2nd November 2015)

• Record Type: Journal Article
• Authors: Su, Feifei; Wu, Fulong; Tang, He; Wang, Zhonghua; Wu, Fanhong
• Is Part Of: Journal of labelled compounds & radiopharmaceuticals. Volume 58:Number 13/14(2015)
• Page Start: 479
• Page End: 482
• Publication Date: 2015-11-02
• Subjects: deuterium labeling -- drug standards -- ractopamine -- β‐adrenergic agonists; Tracers (Chemistry) -- Periodicals; Radiopharmaceuticals -- Periodicals; 615.8424
• DOI: 10.1002/jlcr.3355
• Languages: English
• ISSNs: 0362-4803

Abstract

Abstract : A novel synthetic route to stable deuterium labeled ractopamine was disclosed with 6.49% total yield and 97.7% isotopic abundance. Its structure and the isotope‐abundance were confirmed according to 1 H‐NMR and high‐resolution mass spectrometry. Abstract : A novel synthetic route to stable deuterium labeled ractopamine was disclosed with 9 steps, 6.49% total yield and 97.7% isotopic abundance. Its structure and the isotope‐abundance were confirmed according to 1 H‐NMR and high‐resolution mass spectrometry.