Laser Machined Plastic Laminates: Towards Portable Diagnostic Devices for Use in Low Resource Environments. Issue 11 (15th July 2015)

• Record Type: Journal Article
• Authors: Harper, Jason C.; Carson, Bryan D.; Bachand, George D.; Arndt, William D.; Finley, Melissa R.; Brinker, C. Jeffrey; Edwards, Thayne L.
• Is Part Of: Electroanalysis. Volume 27:Issue 11(2015:Nov.)
• Page Start: 2503
• Page End: 2512
• Publication Date: 2015-07-15
• Subjects: Low‐resource environment bioanalytics -- laser ablated plastic laminates -- electrode arrays -- DNA detection -- orthogonal biosensor; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201500359
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: Despite significant progress in development of bioanalytical devices cost, complexity, access to reagents and lack of infrastructure have prevented use of these technologies in resource‐limited regions. To provide a sustainable tool in the global effort to combat infectious diseases the diagnostic device must be low cost, simple to operate and read, robust, and have sensitivity and specificity comparable to laboratory analysis. In this mini‐review we describe recent work using laser machined plastic laminates to produce diagnostic devices that are capable of a wide variety of bioanalytical measurements and show great promise towards future use in low‐resource environments. Abstract :