An Expedient Access to γ‐Ketophosphine Chalcogenides via the Chemo‐ and Regioselective Addition of Secondary Phosphine Chalcogenides to β, γ‐Ethylenic Ketones. Issue 6 (6th August 2015)

• Record Type: Journal Article
• Authors: Artem'ev, Alexander V.; Malysheva, Svetlana F.; Belogorlova, Nataliya A.; Protzuk, Nadezhda I.; Albanov, Alexander I.; Bagryanskaya, Irina Yu.; Schmidt, Elena Yu.; Gusarova, Nina K.; Trofimov, Boris A.
• Is Part Of: Heteroatom chemistry. Volume 26:Issue 6(2015)
• Page Start: 455
• Page End: 462
• Publication Date: 2015-08-06
• Subjects: Heterocyclic chemistry -- Periodicals; 547.59
• DOI: 10.1002/hc.21281
• Languages: English
• ISSNs: 1042-7163

Abstract

ABSTRACT: γ‐Ketophosphine chalcogenides, precursors for plethora of novel functionalized phosphine chalcogenides and phosphines, are synthesized by chemo‐ and regioselective addition of secondary phosphine chalcogenides to β, γ‐ethylenic ketones under catalyst‐ and solvent‐free conditions (80–100°C, 8–70 h) in excellent yields. The straightforward superbase‐catalyzed synthesis of starting β, γ‐ethylenic ketones from ketones and acetylenes insures the expedient access to the target γ‐ketophosphine chalcogenides.