A novel switched frequency 3He/1H high‐pass birdcage coil for imaging at 1.5 tesla. Issue 4 (6th October 2015)

• Record Type: Journal Article
• Authors: Pratt, Ronald; Giaquinto, Randy; Ireland, Christopher; Daniels, Barret; Loew, Wolfgang; Higano, Nara; Cao, Xuefeng; Thomen, Robert; Woods, Jason; Dumoulin, Charles L.
• Is Part Of: Concepts in magnetic resonance. Volume 45:Issue 4(2015:Nov.)
• Page Start: 174
• Page End: 182
• Publication Date: 2015-10-06
• Subjects: switched frequency MRI coil -- birdcage coil -- hyperpolarized 3He imaging -- NICU MRI; Magnetic resonance -- Periodicals; Nuclear magnetic resonance -- Periodicals; Biomedical engineering -- Periodicals; Magnetic Resonance Spectroscopy -- Periodicals; 538.36
• DOI: 10.1002/cmr.b.21309
• Languages: English
• ISSNs: 1552-5031

Abstract

ABSTRACT: The ability to produce hyperpolarized noble gases 3 He and 129 Xe has opened up exciting possibilities for pulmonary magnetic resonance imaging (MRI). We have recently built a hyperpolarizer with the goal of using hyperpolarized 3 He gas for MRI in neonatal lungs in a dedicated small foot‐print 1.5 T MR scanner developed at our institution and sited in our Neonatal Intensive Care Unit. Although hyperpolarized gas imaging can provide unique insights into lung ventilation, acinar microstructure, and gas‐exchange dynamics, there is an undiminished need for 1 H MRI of the lung to provide anatomic references, B 1 and B0 maps, and 1 H images of lung parenchyma. To address this need, we designed, built and tested a novel radiofrequency body coil that provides a high‐pass birdcage coil that can be used for both 3 He and 1 H frequencies (48.65 and 63.86 MHz, respectively, at 1.5 T). To switch between frequencies, the birdcage coil has a large mechanical actuator that simultaneously changes the capacitance between every rung of the birdcage. Advantages of this coil design include: 1) quadrature excitation and reception at the 3 He and 1 H frequencies, 2) identical B 1 field maps for 3 He and 1 H imaging, 3) excellent signal‐to‐noise ratio and B 1 homogeneity at both frequencies, and 4) rapid (10–20 s) switching times between 3 He and 1 H operation. This report provides details of the coil's design and fabrication. Images of hyperpolarized 3 He and 1 H in phantoms and ex vivo rabbit lungs demonstrate the image quality obtained with the coil. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 174–182, 2015