The Design and Synthesis of Novel 2, 3‐Dihydrobenzo[f]isoquinolin‐4(1H)‐ones via Sequential Ugi–Heck Reactions by Using an Efficient Heterogeneous Palladium Nanocatalyst. (15th December 2014)

• Record Type: Journal Article
• Authors: Rasouli, Mohammad Ali; Miri, Simin; Rashidi Ranjbar, Parviz
• Is Part Of: Journal of heterocyclic chemistry. Volume 52:Number 6(2015)
• Page Start: 1864
• Page End: 1870
• Publication Date: 2014-12-15
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.2270
• Languages: English
• ISSNs: 0022-152X

Abstract

Abstract : A facile and efficient synthesis of N ‐alkyl‐2‐(1, 2 dihydro‐1‐methylene‐4‐oxobenzo[f] isoquinoline‐3(4H)‐yl)‐2‐phenylacetamides is performed by the consecutive, two‐step procedure that consists of Ugi and Heck reactions. The Heck reaction was performed both by homogenous and a designed heterogeneous catalyst. The heterogeneous catalyst is a coordinated palladium to 1, 10‐phenanthroline attached to chitosan@Fe3O4 magnetite nanoparticles, which was shown to be more efficient than the homogenous Pd(OAc)2 /PPh3 catalyst with good to excellent yields. Abstract :