Assessment of human sinus cavity air volume using tunable diode laser spectroscopy, with application to sinusitis diagnostics. Issue 11 (20th May 2015)

• Record Type: Journal Article
• Authors: Huang, Jing; Zhang, Hao; Li, Tianqi; Lin, Huiying; Svanberg, Katarina; Svanberg, Sune
• Is Part Of: Journal of biophotonics. Volume 8:Issue 11/12(2015)
• Page Start: 985
• Page End: 992
• Publication Date: 2015-05-20
• Subjects: paranasal cavities -- frontal sinus -- GASMAS -- water vapor -- sinusitis -- antibiotic resistance; Photonics -- Periodicals; Optical materials -- Periodicals; Optics -- Periodicals; Medical instruments and apparatus -- Periodicals; 621.3605
• DOI: 10.1002/jbio.201500110
• Languages: English
• ISSNs: 1864-063X

Abstract

Abstract : Sinusitis is a very common disease and improved diagnostic tools are desirable also in view of reducing over‐prescription of antibiotics. A non‐intrusive optical technique called GASMAS (GAs in Scattering Media Absorption Spectroscopy), which has a true potential of being developed into an important complement to other means of detection, was utilized in this work. Water vapor in the frontal sinuses, related to the free gas volume, was studied at around 937 nm in healthy volunteers. The results show a good stability of the GASMAS signals over extended times for the frontal sinuses for all volunteers, showing promising applicability to detect anomalies due to sinusitis. Measurements were also performed following the application of a decongestion spray. No noticeable signal change was observed, which is consistent with the fact that the water vapor concentration is given by the temperature only, and is not influenced by changes in cavity ventilation.Evaluated GASMAS data recorded on 6 consecutive days show signal stability for the left and right frontal sinus in one of the test volonteers. Abstract : A non‐intrusive optical technique called GAs in Scattering Media Absorption Spectroscopy (GASMAS) is utilized to study the water vapor in the frontal sinuses of healthy volunteers at around 937 nm. The results, relating to free gas volume, show a good stability of the GASMAS signals over extended times for all volunteers, establishing the applicability of the technique in detecting anomalies due to sinusitis.