The relationship between the frequency of self‐monitoring of blood glucose and glycemic control in patients with type 1 diabetes mellitus on continuous subcutaneous insulin infusion or on multiple daily injections. Issue 6 (25th May 2015)

• Record Type: Journal Article
• Authors: Murata, Takashi; Tsuzaki, Kokoro; Yoshioka, Fumi; Okada, Hiroshi; Kishi, Junichiro; Yamada, Kazunori; Sakane, Naoki
• Is Part Of: Journal of diabetes investigation. Volume 6:Issue 6(2015:Dec.)
• Page Start: 687
• Page End: 691
• Publication Date: 2015-05-25
• Subjects: Diabetes -- Periodicals; Diabetes -- Research -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462005
• DOI: 10.1111/jdi.12362
• Languages: English
• ISSNs: 2040-1116

Abstract

<abstract abstract-type="main" id="jdi12362-abs-0001"> <title>Abstract</title> <sec id="jdi12362-sec-0001" sec-type="section"> <title>Aims/Introduction</title> <p>We investigated the relationship between the frequency of self‐monitoring of blood glucose (SMBG) and glycemic control in type 1 diabetes mellitus patients on continuous subcutaneous insulin infusion (CSII) or on multiple daily injections (MDI) using data management software.</p> </sec> <sec id="jdi12362-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>We recruited 148 adult type 1 diabetes mellitus patients (CSII <italic>n</italic> = 42, MDI <italic>n</italic> = 106) and downloaded their SMBG records to the MEQNET<sup>™</sup> SMBG Viewer software (Arkray Inc., Kyoto, Japan). The association between the SMBG frequency and the patients' hemoglobin A1c (HbA1c) levels was analyzed using the χ<sup>2</sup>‐test and linear regression analysis was carried out to clarify their relationship.</p> </sec> <sec id="jdi12362-sec-0003" sec-type="section"> <title>Results</title> <p>The odds ratio of achieving a target HbA1c level of <8% (63.9 mmol/mol) was significantly higher in subjects with SMBG frequencies of ≥3.5 times/day compared with those with SMBG frequencies of <3.5 times/day in the CSII group (odds ratio 7.00, 95% confidence interval 1.72–28.54), but not in the MDI group (odds ratio 1.35, 95% CI 0.62–2.93). A significant correlation between SMBG frequency and the HbA1c level was detected in the CSII group (HbA1c [%] = –0.24 × SMBG frequency [times/day] + 8.60 [HbA1c {mmol/L} = –2.61 × SMBG frequency {times/day} + 70.5], [<italic>r</italic> = –0.384, <italic>P </italic>= 0.012]), but not in the MDI group.</p> </sec> <sec id="jdi12362-sec-0004" sec-type="section"> <title>Conclusions</title> <p>A SMBG frequency of <3.5 times per day appeared to be a risk factor for poor glycemic control (HbA1c ≥8%) in type 1 diabetes mellitus patients on CSII.</p> </sec> </abstract>